Find your place along the Upper Mississippi River. Our cozy Mississippi River vacation rentals include beautifully renovated cabins and homes in Wisconsin and Minnesota. Relax by the river, explore the outdoors, and experience genuine Midwestern hospitality. Families have been making memories here for over 50 years.
From our Riverside Cabins, perfect for fishing and kayaking, to the spacious Grandview Manse built for multigenerational gatherings, or our Parkside Bungalow near Lake Winona, Big River Escapes has the spot to reconnect with family, get outside, and discover what makes the Upper Mississippi River Valley special.
5 BDR | SLEEPS 16+ | ADA ACCESSIBLE
A bluffside retreat with stunning Mississippi River views located in Minneiska, Minnesota. Perfect for multigenerational gatherings that want space to spread out and create memories.
What makes it special:
Perfect for: Large family reunions, multigenerational getaways, accessible lodging needs
7 CABINS | 2 CAMPERS | DOCK | FIRE PITS
Cozy riverfront cabins in Buffalo City, Wisconsin, with direct river access for kayaking, fishing, and watching the sun set over the Mississippi. Rent one cabin or the entire property for a reunion or group stay.
What makes it special:
Perfect for: Fishing trips, family getaways, small group reunions, and outdoor enthusiasts
3 BDR | SLEEPS 6 | FENCED YARD
A pet-friendly 3-bedroom home near Lake Winona in Winona, Minnesota, with a fenced yard, fire pit, and easy access to Winona State University, downtown, and river activities.
What makes it special:
Perfect for: College visits, art festival weekends, pet-friendly stays, small families
The Upper Mississippi River Valley is more than a destination. It is a landscape shaped by time, dramatic limestone bluffs, winding backwaters, and natural beauty in every season.
Our three properties put you close to the best of the recreational water access. Stay along the river at Riverside Cabins, enjoy bluffside views at Grandview Manse, or explore lakeside trails near Parkside Bungalow. Your next adventure is never far away.
Paddle quiet backwaters as eagles soar overhead. Bike the Great River Road through historic river towns. Explore local wineries tucked into the hills. Or relax on the deck and watch the river roll by.
We are family owned and locally rooted. We know this region and the places that make it special. Let us help you discover them.
Cast for walleye, bass, and catfish in Mississippi backwaters
Kayaking and canoeing through quiet channels
Part of the Mississippi Flyway migration route
Bike or drive the legendary Great River Road
Explore antique shops, cafes, and local character
Plenty of dining options, fun bars and local wineries to enjoy.
Bring the entire family to any one of the Big River Escape properties and discover everything the upper Mississippi River small towns have to offer.
At Big River Escape Riverside Cabins in Buffalo City, you can rent a few cabins or book the entire property. With seven cabins, two campers, riverfront access, fire pits, and a shared pavilion, there’s room for everyone to reconnect. Paddle from our dock, fish the backwaters, play volleyball, or just gather around the fire as the sun drops behind the bluffs.
At Grandview Manse in Minneiska, host up to 16+ guests under one roof. This spacious, ADA-accessible home sits on the bluffs with sweeping views of the Mississippi. A big open kitchen, multiple living areas, and a massive deck make it easy to be together—or find your own quiet corner when you need it.
Both properties are right on the Great River Road, surrounded by river towns, wineries, trails, and some of the best birdwatching on the Upper Mississippi Flyway.
This is where families slow down, reconnect, and create memories that last for generations.
Select your dates below to see available properties and start planning your Mississippi River adventure.
